EG.5 (ERIS) sub-variant COVID clade off-shoot of XBB; this is a ‘nothing burger’ fear-porn, low-risk, yes, more infectious as we expect, yes, evades immunity (antigenic sin, imprinting) mismatch

to existing vaccine and boosters, yet there is no data, NONE to say it is more dangerous, same as Omicron; we however run risk with sub-optimal immune pressure to drive new lethal variants
IMO bringing that XBB.1.5 booster in September will be disastrous and will do much damage and drive this (these variants and the fear porn) to continue for decades. IMO this is deliberate. Done deliberate.
The very same disaster we caused with the in toto across the board, across all age-groups MASS vaccination of the population into the teeth (in the midst) of an ongoing pandemic (it is like loading your gun while the enemy was on the battlefield) where there was MASSIVE infectious pressure (from circulating virus (still is)) while there was MASSIVE mounting immune pressure (mounting population immunity) that was sub-optimal; the immune response (vaccine-induced antibodies (Abs)) could not reach MAXIMAL affinity, full binding capacity for the target antigen (epitopes binding domains e.g. infectiousness of the virus) and as such PRESSURED the virus somewhat (the infectiousness of the virus aka the spike) yet could not STERILIZE the virus (in other words, the Abs could not NEUTRALIZE the virus) and thus could not stop infection, replication, and importantly, TRANSMISSION.

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If you cannot cut the chain of transmission, you cannot get to herd immunity, you cannot end the pandemic. Any epidemic or pandemic.
The result was (when the vaccine was brought Feb 2021) viral immune escape and the vaccinated got infected and re-infected and there was SELECTIVE pressure and as such, variants that could OVERCOME the sub-optimal immune pressure, were selected as they were deemed the FITTEST and HARDIEST and they became the new DOMINANT variants and were ENRICHED in the environment.
The very same INSANITY will occur here by December 2023 if this XBB.1.5 booster is rolled out in the midst of new clades such as EG.5 and as CDC chart shows, other emerging clades such as XBB.2.3, XBB.1.16, and FL.1.5.1.
This remains a disaster in the making, the very same way the new bi-valent booster they more recently brought based on 8 mice, and based on the initial Wuhan legacy strain and the BA.4 and BA.5 clades, while NOT the dominant circulating clades. The result, all who took the bivalent booster got re-infected, it FAILED. Near instant, and people got sick, ill, and many died. Immunity waned near immediately. Especially vulnerable people.
The very same will happen here, due to original antigenic sin (recalled vaccine-induced antibodies will be to the initial prime or exposure (Wuhan strain), immune priming, fixation, prejudice, and the risk of antibody-dependent enhancement of infection (ADEI) and antibody-dependent enhancement of disease (ADED).
The coming XBB.1.5 booster will be DOA, will fail and will drive more variants to emerge, the key being potentially emergence of a more lethal variant.
IMO those involved with the vaccine in all aspects, do KNOW this. It is a combination of ineptness and malfeasance. IMO.

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Author: Dr. Paul Alexander